It's a known issue:
- Quest Mode freezing during load (We have a fix internally that will be included in the next patch)
Potential Workaround: Using groups of size 1-3 has some success. Issue seems to exist more frequently for groups of 4 or larger.
See this post
I only has a party 1-2 and it always freezes on me. I am on hold
Also there are other bugs and other stuff I listed over BGG w;hich need to be fixed
BTW, I like playing one character per area way, which seems to speed things up. But when I draw a card which is impossible to obtain (say it does a divinity check but my character has this rating too low, what should do?